How can cloning help endangered animals




















And second, even if scientists could inspect the yolk on a microscopic level, finding that tiny nucleus floating somewhere in the yolk is extremely challenging. Novak has described the process as akin to "looking for a white marble in a pool of milk. Another issue with eggs is that once the yolk leaves the ovary, it is always on the move. Birds have no such incubation chamber.

There is no uterus equivalent in which to stick a bird clone embryo. Currently, without the ability to cryopreserve the cells of bird species and clone them later, there is no scientific failsafe for birds like there is for mammals in case of genetic bottlenecks or critical endangerment.

However, Jensen is hoping a different emerging genetic technology could perform a similar role for endangered bird species. This one focuses not on creating an entire clone, but on altering what kinds of chicks an individual is producing. That requires researchers to focus on birds' testes and ovaries, also called the gonads. Cloning a mammal involves inserting the DNA of one individual into one egg, and producing one offspring that is the genetic replica of the donor.

Reseearchers refer to these hybrid animals as chimeras. To make a chimera, researchers carefully insert PGCs from a donor into a host embryo as it is developing. If everything goes to plan, the host will grow up to become an adult that produces sperm or eggs containing the DNA of the donor. So, for instance, you might have a domestic rooster host who produces sperm with the DNA of a Greater Prairie-Chicken.

If the rooster were mated with a female Greater Prairie-Chicken, the pair could then produce Greater Prairie-Chicken chicks. This approach has the benefit that one host parent could theoretically produce many offspring with the DNA of a donor over the course of its lifetime, rather than the single individual that would be produced via cloning.

And, as long as researchers can cryopreserve these PGCs, this can still offer the benefit of bringing back DNA from a donor that died long ago. Researchers have made some progress, however, that makes Jensen and Novak hopeful that the technology could one day be used for conservation.

Most of the research thus far has involved domestic chickens. Several groups of researchers have successfully transferred PGCs from one breed of chicken into another, producing offspring with donor DNA.

Researchers have also used the technique to successfully produce Maya Ducks, Korean Pheasants, and even Houbara Bustards by mating chimera domestic chicken males to the females of those species. Perhaps the most notable clone in recent history, Dolly the Sheep, was the first mammal to be cloned from an adult cell.

The first endangered animal to be cloned was the Gaur in But along with these successes were many failed and forgotten clones. Even the cloning of common, well-understood animals is difficult. Dolly the Sheep was the result of the th cloning attempt and only lived to just over half the average lifespan of a sheep.

When the animals are endangered and their reproductive physiology is not well understood, cloning gets even more difficult. Cloning of endangered species has a wildly low success rate; usually under one percent. Even successful clones are often not able to themselves reproduce and usually live shorter than average lives. Because of the potential for reducing the already low numbers of existing population of endangered species, scientists often use close relatives for eggs and as mothers to gestate the cloned embryos.

This often results in the mother rejecting the egg or if the clone is born, reproductive complications. Due to such inefficiencies, most environmental leaders are not bullish on cloning endangered species. Despite not being a viable current method for saving endangered animals, cloning could very well be effective in the future.

In the meantime, and as Ryder points out, efforts to stop poaching and the destruction of habitats—rather than high-tech fixes like cloning—could go much further to preserve species. To donate, visit www. This infusion of genetic diversity could help the animals reproduce more easily and be more resilient to diseases and stressors.

All rights reserved. Now, meet Elizabeth Ann, the black-footed ferret. Making a clone The cloning process began by taking eggs from sedated domestic ferrets, a related species, which were used to avoid putting endangered female black-footed ferrets at risk.

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